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November 12, 1932

Le mycosis fongoïde: Granulomes fongoïdes et sarcomes fongoïdes.

JAMA. 1932;99(20):1715. doi:10.1001/jama.1932.02740720069038

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The literature is reviewed, along with personal observations and experimentation, and the work is divided into historical, clinical, histologic, experimental, hematologic, diagnostic and etiologic, followed by conclusions. The purpose of the work is to emphasize the necessity of considering mycosis fungoides as a distinct entity, although the author admits many similarities with leukosarcomas and lymphosarcomas. Mycosis fungoides comprises a series of disorders of the reticulo-endothelial system of the skin. Granuloma fungoides is an inflammatory reaction, and the tumor stage is the result of a neoplastic change. The systemic reaction of the patient is different in the two conditions. The granulomatous stage may change over into the tumor stage, and for that reason the author prefers to call mycosis fungoides a granulosarcoma. The clinical photographs are good but the photomicrographs are only fair. A bibliography is appended.

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