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Article
December 26, 1953

EVALUATION OF ADRENAL RESECTION AND SYMPATHECTOMY IN NINETY-NINE PERSONS WITH HYPERTENSION

Author Affiliations

Philadelphia
From the Edward B. Robinette Foundation, Medical Clinic, and the Surgical Service of the Hospital of the University of Pennsylvania.

JAMA. 1953;153(17):1502-1505. doi:10.1001/jama.1953.02940340004002
Abstract

This study was begun in March, 1950, after a subtotal adrenalectomy was completed in a patient in whom severe hypertension had recurred one year after a thoracolumbar sympathectomy was performed. As our series of patients increased, we reported encouraging results 1 after employing various types of sympathectomy and various degrees of adrenal resection. This analysis includes 99 such patients followed for from 1 to 37 months after operation. It is our present feeling that sympathectomy combined with adrenalectomy is more effective than either sympathectomy or adrenalectomy alone. We feel, however, that further observations are required to prove or disprove this impression.

INDICATIONS AND CONTRAINDICATIONS  We have required that all three of the following indications be present before operation is attempted. 1. Average diastolic blood pressures should be 120 mm. Hg or more. 2. There should be failure to respond to intensive medical therapy. 3. There should be evidence of progressive

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