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April 15, 1950

Undersøgelser over Aneurinudskillelsen i Urinen hos sunde og syge Børn

JAMA. 1950;142(15):1249. doi:10.1001/jama.1950.02910330131033

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This book is Dr. Schondel's doctoral dissertation. It reports the study of the daily urinary thiamine excretion of healthy infants and children given customary hospital or institution diets, compared with the excretion of 20 normal adults and of a large number of children suffering from various diseases. Urinary thiamine excretion was determined also after administration of 1 mg. of thiamine to children under 3 years of age and 2 mg. to older children. For this study twenty-four hour determinations were recorded for several days after the thiamine administration. The thiochrome method of Westenbrink and Goudschmidt was used throughout, and the data were treated statistically. No correlation was observed between thiamine and body weight, sex or season. The data for the normal group are summarized here:

The daily intake of thiamine approximated 58 micrograms per hundred calories. After the loading test, infants under 3 months excreted an average of only 6

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