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July 15, 1939


JAMA. 1939;113(3):235. doi:10.1001/jama.1939.02800280047012

Carrión's disease is also known under the names of verruga peruana (chronic stage) and Oroya fever (acute stage). The identity of the two conditions (verruga and fever) was dramatically demonstrated by Carrión in 1885 and confirmed afterward by various workers, among them Noguchi, and by Rebagliati and Gastiaburu. Barton found the causative agent in 1909, which Strong and the Harvard commission named Bartonella bacilliformis in his honor in 1913. Battistini and Noguchi later grew this organism in cultures.

Because of a number of peculiarities, the two stages (verruga and fever) have long attracted international attention; American scientists have been prominently identified with researches into their etiology and transmission. Only a few months ago a Harvard University commission returned from a field study of the disease in Peru. One point usually emphasized is the geographic limitation of the condition; until recently it was definitely identified only in the rather sharply defined