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July 15, 1939

Cholesterol Content of the Red Blood Cells in Man

JAMA. 1939;113(3):255. doi:10.1001/jama.1939.02800280067026

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Abstract

To research workers and clinicians this book presents in extreme detail the author's investigations on the significance of the cholesterol content of the red blood cells in man. An excellent review of previous work is given together with a criticism of existing analytic procedures. The author has worked out a modified method which is apparently reliable and which is presented in such detail as to be easily followed by any worker in this field. The fact is demonstrated that, in heparinized blood, lipoid extracts will usually be incomplete unless the hematocrit value is reduced by dilution. It is pointed out that previous values for the cholesterol content of the red cells in man are at extreme variance because of the use of unreliable analytic procedures. Hence the author has established normal values for fifty-eight subjects and treated the data statistically. Normal values as they vary during a month are given

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