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January 11, 1947

Current Comment

JAMA. 1947;133(2):111. doi:10.1001/jama.1947.02880020037014

CANCER TREATMENTS FROM RUSSIA  The KR treatment,1 named after its originators Nina Klyueva and Georgi Roskin, is now being tested in the treatment of human cancer in Moscow, Russia, by Trutnev, Lyampert and Egorov. The method is said to have little effect in cancer of the skin but to show promise in cancer of the throat, uterine cervix and breast. The preparation is made from dead protozoa of the species Trypanosoma cruzi. The material is said to localize in tumors and destroy them. This line of research followed the earlier observations of Roskin that living Trypanosoma cruzi after injection could destroy tumors in mice, although the animals themselves later succumbed to the infection. From the information at hand it is not possible to determine the biologic and chemical principles involved in the preparation and use of this material. Neither can its effectiveness be judged. In a second release2