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Article
November 26, 1932

ROENTGENOTHERAPY OF MALIGNANT NEOPLASMS OF THE PHARYNX AND LARYNX

JAMA. 1932;99(22):1840-1845. doi:10.1001/jama.1932.02740740024007
Abstract

Roentgenotherapy of malignant neoplasms of the pharynx and larynx has up to recently been successful in only occasional instances.1 The results have improved since the principles controlling radiosensitivity have become better understood and a new, more intensive technic of roentgenotherapy has been perfected by Coutard of the Curie Institute of Paris.2

The majority of malignant neoplasms of the pharynx and larynx usually do not spread beyond the head and neck until late in the course of the disease, and the entire cancer-bearing area may thus be included within the field of intensive irradiation. For the correct application of this treatment, familiarity with the microscopic observations, the gross anatomy and the clinical behavior of the neoplasm to be treated is essential.

Most neoplasms of the pharynx and larynx arise from the mucosa. The epithelium covering this region is epidermoid in character except in the nasopharynx and below the vocal

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