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May 6, 1950


Author Affiliations

Huguenot, S. I., N. Y.

JAMA. 1950;143(1):23. doi:10.1001/jama.1950.82910360006008b

In spite of statistical evidence to the contrary, there persists general acceptance of the belief that congenital abnormalities are unlikely to recur. In a recent inquiry to The Journal1 regarding recurrence of hydrocephalus an opinion was given that the parents of a monstrosity run no greater risk of having another one than any other parents. This was challenged by Murphy,2 who studied the outcome of all conceptions in a series of 890 women, each of whom had given birth to a congenitally malformed child. A case of recurrent anencephaly, the report of which follows, emphasizes some of the inherent problems.

REPORT OF CASE  I. R., primigravida aged 21, was seen July 14, 1947, with a history of last menstruation on April 8, 1947. Her past history revealed no illnesses, surgical operations or accidents. Family history of both the patient and her husband and of all siblings revealed no