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July 29, 1939


JAMA. 1939;113(5):416. doi:10.1001/jama.1939.02800300046013

Eppinger1 in 1881 gave the first complete anatomic description of tuberculous tracheal ulceration, pointing out the tendency of the ulcers to localize in the lower part of the trachea. In about one eighth of his necropsies the lesions were not associated with tuberculous laryngitis. He believed they were an extension from the adjacent tuberculous lung tissue and caseating peribronchial lymph nodes. Despite this excellent description, tracheobronchitis as a complication of pulmonary tuberculosis received but scant attention in the succeeding decades. With the revival of interest in tracheobronchial tuberculous disease, a number of studies of necropsy material have become available. Reichle and Frost,2 on the basis of microscopic examination of the tracheobronchial tree in thirty-seven cases in which death occurred from chronic phthisis, concluded that the common modes of infection of the major bronchi are by contiguity from the diseased lymphatics and lymph nodes of the peribronchial tissue or