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July 29, 1939

Die endokrinen Drüsen des Gehirns: Epyphyse und Hypophyse. Ein Blick in ein interessantes Gebiet

JAMA. 1939;113(5):447. doi:10.1001/jama.1939.02800300077037

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Abstract

This is a review of the laboratory and clinical knowledge concerning the epiphysis and hypophysis, mainly the latter. Twenty-five separate pituitary hormones are accepted and discussed by the author. For each hormone the history, origin, function, deficiency and excess manifestations, clinical conditions in which it is involved and medical and surgical treatment are outlined. Unfortunately the author fails to sift or evaluate the literature reviewed, so that in consequence the book is a collection of fact and fiction which has accumulated for the past hundred years. Many general conclusions and dogmatic statements are made concerning problems and observations which are still unsubstantiated. Much significant laboratory and clinical work concerning the hypophysis is not mentioned. Treating endocrine deficiencies by transplanting animal glands is the recurrent theme. The author's own work in transplantation figures largely in the book, although this method has not had recognition in the literature. There is no bibliography.

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