Torulae are yeast-like fungi which occur widely disseminated in nature. They are found on trees, flowers, fruits and insects and are of the genus Cryptococcus. The medical significance of this yeast is its pathogenic production of a cystic blastomycosis in man and certain animals. An accurate estimate of the incidence of torulosis is impossible to determine. This is because the condition is not sufficiently well recognized by the profession at large. The report under discussion constitutes the most recent of sixty-four cases appearing in the medical literature. There are probably numerous instances which go unreported because of failure of diagnosis. The protean manifestations of Torula histolytica leads us to believe this disease worthy of special mention.
Robert Hooke1 in 1656 was the first to describe fungous disease. In 1901 Bertarelli and Calamida2 described yeasts as etiologic factors in throat and tonsil infections. Frothingham3 in 1902 reported
ROBERTSON WE, ROBERTSON HF, RIGGS H, SCHWARTZ L. TORULOSIS INVOLVING THE HUMAN CEREBRUM. JAMA. 1939;113(6):482–484. doi:10.1001/jama.1939.02800310020006
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