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Article
December 3, 1932

BISMUTH IN THE TREATMENT OF CARDIOVASCULAR SYPHILIS

Author Affiliations

With the Collaboration of JOSEPH H. BOLAND, A.B. ATLANTA, GA.

From the Emory University School of Medicine, and Grady Hospital.

JAMA. 1932;99(23):1902-1906. doi:10.1001/jama.1932.02740750004002
Abstract

The Emory University School of Medicine for several years has conducted the half of the Grady Municipal Hospital that is devoted to the care of Negroes. This includes a large outpatient department. Shortly after beginning to teach in this dispensary in September, 1928, I was struck with the prevalence of congestive heart failure associated with syphilis. One of these early patients was treated with mercury, potassium iodide and digitalis for about six months without improvement. Finally, I resorted to bismuth arsphenamine sulphonate (bismarsen), and a month later the patient returned to heavy labor. He has had two minor recurrences of congestive failure, and has returnedto the dispensary for a few treatments. He is still living and working. This unexpected result interested me in the treatment of cardiovascular syphilis.

While not attempting to maintain a clinic for general syphilis, I have tried to treat about three hundred patients with cases of

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