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June 3, 1950

ORALLY GIVEN MEPHENESIN IN INFANTILE CEREBRAL PALSY

JAMA. 1950;143(5):424-426. doi:10.1001/jama.1950.02910400016005
Abstract

The treatment of cerebral palsy at the present time centers about muscle relaxation and reeducation. The modalities employed in training a child are well defined and are executed in specific phases during the progress of a patient. The training period is long and tedious and may well be compared in chronicity to the educational program of a normal child in his primary school. Surgical procedures, external bracing and medication are considered adjuncts only.

Many children manifesting the various types of cerebral palsy have been subjected to the administration of barbiturates, belladonna, scopolamine, stramonium, neostigmine and other preparations in the hope of release from the abnormal state. The results over a long period of time have been variable if not indifferent.

A definite aid in treatment might be a nontoxic drug with few or no undesirable effects. Such a preparation should be palatable to children. It should produce the desired degree

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