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Article
March 13, 1954

EVALUATION OF TOXICITY OF CHEMICALS

JAMA. 1954;154(11):938-939. doi:10.1001/jama.1954.02940450058024

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Abstract

To the Editor:—  I refer to the article "Perspective Versus Caprice in Evaluating Toxicity of Chemicals in Man" by Dr. M. H. Seevers in the Dec. 12, 1953, issue of The Journal. It makes a highly valuable contribution in the clear and logical statement of five principles on which the evaluation of toxicity in human beings must be based. This is a splendid guide in considering the use of chemicals in foods. Dr. Seevers' distinguished work in pharmacology has been known for many years. It is regrettable that the over-all value of the article is impaired by a number of erroneous assertions and implications in the discussion preceding the statement of principles. Most glaring of these is the assertion that, "For approximately 50 years, the food division of the Food and Drug Administration has adhered to a basic administrative policy that no chemical shall be added to foods." There is

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