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March 29, 1947

Current Comment

JAMA. 1947;133(13):940. doi:10.1001/jama.1947.02880130040013

EFFECT OF VACCINATION ON INCIDENCE OF INFLUENZA B  Hirst and his colleagues1 have studied the value of influenza vaccination in an epidemic of influenza B. They compared a group of 550 men attending Yale University as part of their Army Special Training Program who had received mixed A and B influenza vaccine with a group of 1,050 unvaccinated naval students studying at the same institution under similar circumstances. In the early part of November 1945 an epidemic of influenza caused almost entirely by the B virus developed. The number of cases reached a peak in about four weeks and was rapidly subsiding by the middle of December. Three cases of influenza appeared in the vaccinated group and 132 cases in the unvaccinated group, giving attack rates of 0.5 and 12.5 per cent respectively. The investigators believe it highly probable that the difference in attack rate could be attributed to