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The material of this book is the outgrowth of many sciences, and the success or failure of accomplishing the titular task of relating chemical constitution to biologic activity depends as much on the status of current knowledge in such wide fields as chemistry, biology and physics as it does on the ability of the author. Although it is possible now to establish many links between chemical constitution and biologic activity, it will become obvious to the reader that many gaps still remain. This is not surprising, considering that the bulk of present knowledge of this field is the result of research carried out within the last two decades. It is heartening to note, however, that the acceleration of research and the accumulation of new literature is so rapid that the author found it necessary to set the middle of 1947 as the deadline for receipt of papers to be considered
Chemical Constitution and Biological Activity. JAMA. 1950;143(7):691–692. doi:10.1001/jama.1950.02910420079041
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