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June 24, 1950


Author Affiliations

Professor of Hygiene and Preventive Medicine, University of Toronto.

JAMA. 1950;143(8):761. doi:10.1001/jama.1950.02910430053025

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To the Editor:—  In the article entitled "Postoperative Tetanus" by Henry J. van Duine in The Journal May 13, 1950, the following statement appears in the conclusion: "A year later the immunity can be boosted by either toxoid or toxin." I feel that this statement should have been challenged by the Editor before appearing in print. It is perhaps technically possible to utilize toxin as a booster dose, e. g., a Schick test in the case of diphtheria. No person would, however, have the temerity to use toxin for the purpose implied. No preparation of either tetanus or diphtheria toxin for this purpose is licensed by any department of government as far as I am aware.

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