[Skip to Content]
[Skip to Content Landing]
April 26, 1947


JAMA. 1947;133(17):1301. doi:10.1001/jama.1947.02880170047021

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


To the Editor:—  The Journal has come to occupy a well deserved place as the major, if not the only, medical periodical read by the average general practitioner in this country. This places a heavy responsibility on contributors, as their procedures, technics, dosages and sometimes even minor suggestions may be adopted in toto by a practitioner too busy to investigate further. For this reason it is disturbing to us as pharmacologists to see important fundamental principles overlooked in an article published in The Journal.In a communication entitled "Prolonged Reaction to Benadryl" by Samuel Schwartzberg and Darrell Willerson (The Journal, February 8, p. 393) the authors suggest treatment of a Benadryl reaction with intravenous histamine. This may seem a logical procedure when one thinks of Benadryl only as an antihistamine drug; but drugs, especially those with complex chemical formulas, seldom act on only one system or mechanism. It is probable

First Page Preview View Large
First page PDF preview
First page PDF preview