Under the general caption of the "toxemias of pregnancy" are grouped a variety of functional derangements and organic changes defining a series of pathologic entities not necessarily interrelated but all interfering gravely or completely with the normal course of gestation.
With the diversity of the several better defined conditions included in this group, no common etiologic background can be assumed or demonstrated, and yet they do have in common the fundamental factor of the pregnancy. The improvement demonstrated in the surviving patient at termination of gestation further emphasizes this fact. The betterment ranges from apparent complete recovery in those cases in which no irreversible organic change has taken place to real amelioration of the more distressing features in the graver conditions where irreparable damage has been done. Further, in the course of even rigorously normal pregnancy there are not lacking evidences of lowered or modified function levels which may be
ROWE AW. THE TOXEMIAS OF PREGNANCY: SOME OBSERVATIONS ON THE HEPATIC FACTOR. JAMA. 1932;99(25):2083–2087. doi:10.1001/jama.1932.02740770013003
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