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September 16, 1939

Encefalitis postneumonica en el niño

JAMA. 1939;113(12):1156. doi:10.1001/jama.1939.02800370072036

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This is monograph 3 from the pediatric clinic of Dr. Luis Marquio in Montevideo. Abstracts and tables are given of twenty-eight cases in children ranging in age from 14 months to 12 years. Most of them have previously been published in South American, French and Italian journals. No publications in English or German are mentioned. Of the twenty-eight cases, six terminated fatally. The gross and microscopic lesions in the brain in one case are described and illustrated. On the sixth day of lobar pneumonia a violent convulsion set in followed by coma. The bilateral Babinski sign was present, the knee reflexes were normal and there was no rigidity. The spinal fluid showed no increase in cells or globulin. Death was twenty-seven hours after the onset of brain symptoms. Infiltrative and degenerative changes were found in the striatum and thalamus (while the substantia nigra escaped). The cortex showed only congestion. In

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