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September 30, 1939


JAMA. 1939;113(14):1349. doi:10.1001/jama.1939.02800390071027

To the Editor:—  In The Journal July 8, page 126, appeared an article by Levine and Stetson concerning a case of intragroup agglutination (immune iso-agglutination) after repeated transfusions. It makes no reference to my publication on the same subject in Klinische Wochenschrift, Nov. 14, 1936, page 1675. It must be emphasized that in the European literature there were five cases previous to mine in which sensitization was demonstrable of the red blood cells to blood of its own group. Only Deutsch's case resembled Levine and Stetson's; therein the symptoms of iso-immunization disappeared in a few weeks. In my case all samples of the B group blood cells showed agglutination without exception with the serum of the sensitive patient belonging to the B group, and none of the O group blood cells evidenced these symptoms. So it could be demonstrated by the indirect method that the immunization depends on the B