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October 14, 1939

PRIMARY PERITONITIS IN INFANTS AND CHILDREN: A MORE EFFECTIVE TREATMENT

JAMA. 1939;113(16):1455-1459. doi:10.1001/jama.1939.02800410005002
Abstract

Primary, idiopathic or metastatic peritonitis has always been associated with a very high mortality rate in infants and children. In recent years, with the use of sulfanilamide and antipneumococcus serum, we have markedly lowered the mortality rate in this disease and have revised our therapeutic approach. It is our purpose in this paper to present an effective treatment of the disease and the information gained from sixty-seven cases of primary peritonitis observed in the ten year period 1929-1939 at the Children's Hospital.

ETIOLOGY  The offending organism in primary peritonitis is usually the pneumococcus or the hemolytic streptococcus. Three patients with primary peritonitis, not included in this series, were encountered in whom no organisms were demonstrable by direct smear or culture of the peritoneal exudate. The streptococcus was found more than twice as frequently as the pneumococcus, since there were forty-seven cases attributable to the former and twenty cases to the

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