The occurrence of urinary calculus in a patient who for a period of time has been taking alkalis in the treatment of peptic ulcer may arouse suspicion that the stone has formed as a result of the use of the alkalis. This idea appears to exist not only in the minds of the public but in the minds of some members of the medical profession as well.
The present study was undertaken with a view of securing data from which conclusions might be drawn as to the etiologic relationship, if any, between the use of alkalis in the treatment of peptic ulcer and kidney and ureteral stone formation.
The data that we present were obtained by an examination of the records of 2,210 cases, of which 1,260 cases were seen by one of us (H. L. K.) and 950 by the other (R. C. B.).
Calculous disease dates back
KRETSCHMER HL, BROWN RC. DO ALKALIS USED IN THE TREATMENT OF PEPTIC ULCER CAUSE KIDNEY STONES? A STUDY OF 1,940 CASES. JAMA. 1939;113(16):1471–1475. doi:10.1001/jama.1939.02800410021005
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