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June 14, 1947


Author Affiliations

Nashville, Tenn.

JAMA. 1947;134(7):625. doi:10.1001/jama.1947.02880240061021

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To the Editor:—  In The Journal, April 26, there appeared an editorial comment on eosinophilic granuloma of bone. The statement is made "Neither have any visceral lesions been described, a curious feature inviting close study."I wish to call attention to "Eosinophilic Granuloma of Bone— Report of a Case with Multiple Lesions of Bone and Pulmonary Infiltration" (Arch. Int. Med.79:176 [Feb.] 1947) by Albert Weinstein, Herbert C. Francis and Bertram F. Sprofkin. In this case are described lesions in the lungs which were best explained by the eosinophilic granulomatous lesion which was proved to be the nature of the bone lesions. These pulmonary changes disappeared under x-ray therapy as did the bone lesions. We feel very strongly that this is a true instance, and therefore the initially reported example, of a visceral lesion as part of the clinical picture of eosinophilic granuloma of bone.

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