A simple method of demonstrating the L. E. cell, the diagnostic cell in lupus erythematosus, by finger puncture is presented in this preliminary report. This method takes advantage of the modern refinements in technique for demonstrating the L. E. cell, namely, the use of clotted blood1 and a suitable incubation period.2 Its chief aim is to make the test available to the general practitioner, the internist, or the dermatologist without the special equipment of a laboratory.
The finger is punctured in the usual manner as for the making of blood smears and about 10 drops of blood are collected in a small test tube. The tube we use is about 75 mm. in length and has an internal diameter of 7.5 mm. In such a tube 10 drops of blood would measure about 1/4 in. The blood is allowed to clot at room temperature for four to
Samuel Rosenfeld, A. Irving Swiller, Maurice Morrison. SIMPLE METHOD OF DEMONSTRATING THE L. E. CELL BY FINGER PUNCTURE. JAMA. 1954;155(6):568–569. doi:10.1001/jama.1954.73690240002010a