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August 12, 1950

Proceedings of the First Clinical ACTH Conference

JAMA. 1950;143(15):1378. doi:10.1001/jama.1950.02910500080034

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This volume is a compilation of the work of many investigators during the scant two and one-half years that pituitary adrenocorticotropic hormone (ACTH) has been available. The papers included were presented in October 1949 at the Clinical ACTH Conference held for the purpose of exchange of information on the metabolic, physiologic and clinical effects of the pituitary adrenocorticotropic hormone. Although many of the presentations are only status reports, the book is at present the most important collection of information on the fundamental and possibly far reaching effects of adrenal cortical stimulation.

It is difficult to draw generalizations from a book containing 52 separate monographs; however, for conditions other than rheumatoid arthritis, gout and allergic diseases, too few cases are considered to permit final conclusions on the merits of adrenocorticotropic therapy. Many of the studies lack control series. The dangers of interpretation based on these early experiences can best be illustrated

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