From a review of the literature it is evident that thrombophlebitis of the cavernous sinus is not a rarity. It has been reported in the literature since 1818,1 and until recently it has been 98 per cent fatal. There have been reported instances of recovery since 1869. Some of these recoveries have occurred spontaneously while others have been the result of surgical intervention, which has been a therapeutic procedure since 1902. In all patients who were cured the convalescence was greatly prolonged. Eagleton2 reported a series of 25 cases in which there were 4 recoveries, in 3 of which the patient had surgical therapy. From the late nineteenth century until the onset of chemotherapy 58 recoveries have been reported.3 The exact percentage of recoveries since the onset of chemotherapy is not available, but certainly reports of recovery are much more frequent in the literature.4
BRETHAUER EA. THROMBOPHLEBITIS OF THE CAVERNOUS SINUS: Report of Complete Recovery in Case with Multiple Pulmonary Abscesses Complicating Pregnancy. JAMA. 1947;134(13):1090. doi:10.1001/jama.1947.72880300005009
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: