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September 9, 1950

LIVER CIRRHOSIS IN PARASITIC DISEASES

JAMA. 1950;144(2):185. doi:10.1001/jama.1950.02920020105015
Abstract

An important parasitic disease is due to the blood fluke Schistosoma haematobium. In some countries schistosomiasis causes more sickness and death than any other single disease. It has been estimated that 6 million of the 12 million inhabitants of rural Egypt are infested with S. haematobium and 3 million with S mansoni and that at least one and a half million are infested with both species together (Scott1). Cirrhosis of the liver may follow infestation by these parasites. In Egypt, Symmers2 described a variety of cirrhosis with the presence of ova of Bilharzia. It is characterized by enormous thickening of the periportal connective tissue and is sometimes called "pipestem" cirrhosis. In China, Japan and the Philippines there is a disease known as Asiatic schistosomiasis, which is characterized by cirrhosis of the liver, splenomegaly, ascites, dysentery, progressive anemia and sometimes by focal epilepsy. The disease occurs extensively in one

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