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August 7, 1954


JAMA. 1954;155(15):1366-1367. doi:10.1001/jama.1954.03690330070019

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Treatment of Toxicomania.  —R. Lecoq and his co-workers observed that the repeated oral, subcutaneous, or intraperitoneal introduction of caffeine, alcohol, cocaine, morphine, or nicotine into animals produces an excitation with lowering of the chronaxy, but the intravenous introduction of the same substances if not repeated frequently produces no intoxication. On the contrary, the nervous disorders disappear when this method of administration is used. The authors have, therefore, treated various toxicomanias by this method (Gazette of Hospital, March 31, 1954). Another method of treating morphine addiction consists of injecting decreasing doses of morphine, diluted in glucosic serum. The results have been satisfactory especially in patients who have not already used this method of introducing the drug. For alcoholism, they inject alcohol of 25 degrees in glucosic serum (Curethyl A) in decreasing doses of 200 to 50 cc. per day with vitamins intravenously, or in some patients nicotamide adenine (Curethl B) and

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