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September 6, 1947


JAMA. 1947;135(1):52. doi:10.1001/jama.1947.02890010054023

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To the Editor:—  In the article on Streptomycin Toxicity by my associates and myself in The Journal, June 21, a statement was made that the highly purified streptomycin used in the study was first crystallized in the form of the calcium chloride double salt and "then converted by mild treatment to the sulfate to ensure stability."It has been brought to my attention that it might be inferred from this statement that the calcium chloride double salt of streptomycin is less stable than the highly purified sulfate. It was not intended to convey any such impression; I am reliably informed that no significant difference exists in the stabilities of these two salts of streptomycin.

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