Among the millions of cold wave permanents containing thioglycolate which have been used by women at home and in beauty salons there have been only a few with deleterious effects on the skin and scalp. For the most part these have been considered due to primary irritation from the use of the ammonium salts of thioglycolate, and rarely to eczematous hypersensitivity. The dermatitis is usually found on the forehead, ears and nuchal regions. Fragmentation and splitting of the hair are not uncommon.
We are reporting two cases of temporary baldness following the use of cold permanent waves containing ammonium thioglycolate. The two cold wave permanents were given in different beauty parlors, and two different commercial preparations of ammonium thioglycolate were used. The first patient began to have a regrowth of hair in approximately three weeks; the regrowth of hair in the second woman was visible after twenty days.
REICHES AJ, LANE CW. TEMPORARY BALDNESS DUE TO COLD WAVE THIOGLYCOLATE PREPARATIONS. JAMA. 1950;144(4):305–306. doi:10.1001/jama.1950.62920040003005b
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