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August 14, 1954


JAMA. 1954;155(16):1444. doi:10.1001/jama.1954.03690340066020

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Treatment of Trachoma.  In the Journal of Health, Prof. N. Sezer of Istanbul reported the effects of antibiotics on trachoma among hospital patients and school children. Of 550 children who had trachoma 250 were given oxytetracycline (Terramycin), 250 chloramphenicol (Chloromycetin), and 50 chlortetracycline (Aureomycin). Some patients were given eyewash and some were given capsules. Most of the patients received either 0.5% chlortetracycline, 0.5% oxytetracycline, or 1% chloramphenicol ointment to be rubbed on the lesions five times daily. Seventy per cent of the patients with primary acute trachoma who were given chloramphenicol, and 60% of those who were given oxytetracycline or chlortetracycline ointment recovered; 40 to 50% of those with chronic trachoma who were treated with chlortetracycline, 32 to 55% of those treated with chloramphenicol, and 15 to 20% of those treated with oxytetracycline ointment recovered. Although clinical symptoms sometimes persisted, laboratory investigation showed that in every case these antibiotics

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