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One of the greatest drawbacks to the application of aerosol techniques to medication and experimentation is the impractical method in use today for controlling the feeding stream of fluids into nebulizers. These systems are difficult to regulate, demand constant observation; they are untidy and wasteful of expensive medicaments. There is a real place in medicine, both experimental and therapeutic, for a new and simpler system. The system outlined below has been tested and proved in experiments in which a wide range of fluids of different viscosity were used. In one such experiment three nebulizers were put in operation for eight-hour periods daily, for a total of 1,440 hours without breakdown. The supply of air pressure was turned on in the morning and off in the evening. No other attention was necessary except refilling the fluid reservoirs. Following is an outline of the method and an explanation of the physical principles
Kopf EH. A NEW, SIMPLE, AND PRACTICAL METHOD FOR CONTROL OF FLUIDS USED IN AEROSOL THERAPY. JAMA. 1954;155(18):1578–1579. doi:10.1001/jama.1954.73690360002008a
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