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November 8, 1947

Diseases of Metabolism: Detailed Methods of Diagnosis and Treatment; A Text for the Practitioner

JAMA. 1947;135(10):678. doi:10.1001/jama.1947.02890100072026

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This well known textbook of metabolism will bring the reader strictly up to date concerning last minute laboratory and clinical data in the fundamental physiologic, biochemical and therapeutic approaches to metabolic disorders. This edition represents a thorough revision in the light of the most recent investigative work. The war years contributed vast changes to our knowledge of such subjects as nutrition, and the basic metabolic aberrations coincident to or responsible for disease processes. In this light any pathologic physiology has its metabolic component, and in this textbook the reader will find detailed discussions as far afield as diseases of the kidneys and hematologic disorders.

Sections devoted to carbohydrate, protein and lipid metabolism completely describe digestion, catabolism and anabolism, taking the student through the chain of molecular changes to the liberation of energy and excreted metabolites. Enzyme systems responsible for these molecular alterations are discussed fully and in detail. While this

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