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To the Editor:—
The editorial "Tetanus Immunization" in The Journal of Oct. 2, 1954, page 501, presents certain aspects of this problem in a clear and timely fashion, but it also contains a number of statements that run counter to the vast experience already available bearing on this question. References can readily be cited to the following specific points.1. It is stated that under specified circumstances antitoxin "must be used in addition to the usual booster dose of tetanus toxoid. These indications are: (1) poor general health or the presence of diseases of a debilitating nature; (2) considerable blood loss at the time of injury, as in military combat or vehicle accidents; (3) delay of several days in the administration of an indicated booster dose of toxoid; and (4) the presence of local lesions (compound fractures, severe lacerations, etc.) considered very likely to result in clinical tetanus." The first
Geoffrey Edsall. TETANUS IMMUNIZATION. JAMA. 1954;156(14):1350. doi:10.1001/jama.1954.02950140050019