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January 31, 1948


Author Affiliations

Memorial Hospital and the Sloan-Kettering Institute for Cancer Research New York

JAMA. 1948;136(5):305-308. doi:10.1001/jama.1948.02890220015004

The pattern of recent advances in the treatment of cancer differs somewhat from that of the past. It represents, perhaps, an indication of a new trend, long foreseen, toward more radical surgery on the one hand and toward new biochemical approaches on the other. This denotes a strengthening of the position of surgery as a curative agent, coincidentally with an intensified search for new means of palliation and control.

The procedure devised by Mohs,1 entitled "Chemosurgical Treatment of Cancer," has recently been the subject of a review of five year end results of its application to neoplasms of the ear. The method is beyond question an interesting one and deserving of careful consideration. Of 19 patients with squamous cell carcinoma treated, 9 are well after five years. It is unfortunate that no figure is given for the five year salvage in cases of disease recurrent after efforts at therapy