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January 15, 1955

Biochemical Investigations in Diagnosis and Treatment

JAMA. 1955;157(3):300. doi:10.1001/jama.1955.02950200098036

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This book, written by a clinician, attempts to give younger clinicians, primarily of the resident level, information about the use of biochemical laboratory tests in diagnosis and clinical management of diseases. The author discusses in various chapters disturbances of the metabolism of the electrolytes, including the acid-base equilibrium as well as the metabolism of protein, fat, and carbohydrate with special consideration to diabetes mellitus. There are discussions on diseases of the gastrointestinal tract and the liver; renal function, including examination of the urine and spinal fluid; abnormalities of the endocrine glands; vitamin metabolism; and poisons. Useful tables with normal values in various body fluids are included in the final chapter. Usually a short, concise introduction of the physiological basis precedes a description of the significance of the individual test. Clinically important considerations are frequently included, and a few literature references to standard textbooks accompany each chapter. The book is well

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