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To the Editor:—
It has recently been claimed that oral therapy with large doses of a protein hydrolysate powder (an enzymatic digest of casein containing amino acids and their peptides) supplemented with large doses of cyanocobalamin (vitamin B12) and folic acid has had a restorative effect on the muscles in patients with muscular dystrophy (Van Meter, J. R.: California Med.79:297, 1953; paper read before the sixth annual meeting of the American Academy of Neurology, Washington, D. C., May 1, 1954). Others have not been able to confirm these findings (Drew, A. L., and others: Neurology4:789, 1954).We studied a group of six adult patients with slowly progressive muscular dystrophy of long duration and advanced degree, involving to a greater or lesser extent all four extremities. The diagnosis of muscular dystrophy was made in each case over the course of years by several observers on the
Ziegler DK, von Storch TJC. EVALUATION OF PROTEIN HYDROLYSATE THERAPY IN TREATMENT OF MUSCULAR DYSTROPHY. JAMA. 1955;157(5):466. doi:10.1001/jama.1955.02950220060021
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