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February 5, 1955


Author Affiliations

The National Jewish Hospital Denver 6.

JAMA. 1955;157(6):532-533. doi:10.1001/jama.1955.02950230046024

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To the Editor:—  For many years tuberculosis of the hilar lymph nodes has been considered to be an unimportant, self-regressing entity. Recent studies, however, have shown that hilar nodes are a dangerous and persistent source of complications. It behooves us to treat this condition early and effectively. We are all familiar with the relatively poor response of tuberculosis of the cervical lymph nodes to antimicrobial agents. Surgery and radiotherapy are the current forms of treatment. There is no reason to suppose that hilar lymph nodes should respond any more favorably than cervical nodes. It may be that long term isoniazid therapy will have a beneficial result on tuberculosis of the hilar nodes. Russell, in a recent study, has shown that parenchymal pulmonary lesions are sterile after 15 to 18 months of treatment with isoniazid. He admits, however, that these lesions look worse during the first 12 months, and he has

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