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March 5, 1955

Studies in Schizophrenia: A Multidisciplinary Approach to Mind-Brain Relationships

JAMA. 1955;157(10):871. doi:10.1001/jama.1955.02950270089035

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The concept underlying the research presented in this unusual book is described as: "The over-all effect in schizophrenia can be assumed as one of cortical impairment. As a result of that the subcortex is functioning abnormally. It can be expected that electrical stimulation of the basal parts of the septal region of the brain might stir it into more normal activity, thus facilitating cortical activity and bringing the individual out of the sleeplike state of reverie, helping him to make better interpretation of reality." The main part of the book consists of an extensive description of the procedure for stimulating subcortical parts of the brain and of the behavioral change of the patient during stimulation and during the weeks and months after. It is stressed, that "if also some results in therapy have been achieved, much remains to be done." The results show that the method may be useful, regardless

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