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May 15, 1948


Author Affiliations

President, Cutter Laboratories, Berkeley, Calif.

JAMA. 1948;137(3):322. doi:10.1001/jama.1948.02890370104020

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To the Editor:—  We are reviewing every procedure, and record and testing every piece of equipment in the department involved, but at this moment we still do not know the cause of the contamination in some of the bottles of two lots of dextrose solution. The original tests were satisfactory, and retained samples and stocks remaining in our Berkeley warehouse were not contaminated. Some of the bottles returned from the field were unquestionably contaminated, a contamination which was apparent on visual inspection and viable on culture.This laboratory has over a half century record of safety in the production of bioligicals and other products for parenteral injection. It is a record which neither management nor the men and women of unquestioned capability and integrity who staff the laboratories would wilfully jeopardize. Yet what was to us inconceivable happened. I need not protest of our extreme regret for this most unfortunate

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