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March 19, 1955

Tumours of Lymphoid Tissue

JAMA. 1955;157(12):1068. doi:10.1001/jama.1955.02950290088037

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This monograph is based on studies of 140 patients with tumors of lymphoid tissues. Its 14 chapters discuss structure, function, and significance of lymphoid tissue; historical survey; terminology and classification, incidence of tumors of lymphoid tissue; follicular lymphoma; lymphosarcoma; reticular lymphoma; Hodgkin's disease; reticulum cell sarcoma; anaplastic sarcoma of lymphoid tissue; problems of diagnosis; effects of therapy on primary tumors of lymphoid tissue; general conclusions; and illustrative cases. The author has arranged the tumors of lymphoid tissue into (1) those having lymphocytic differentiation (lymphosarcomas that include lymphatic leukemia with lymph node involvement and follicular lymphomas); (2) those having reticulum cell differentiation—the reticulum cell sarcoma; (3) those with a mixture of cell types that include Hodgkin's disease and reticular lymphoma; and (4) those with imperfect development making impossible a cell-type differentiation. Lumb's account leaves little doubt that Hodgkin's disease is a cancerous growth. The monograph is recommended to pathologists and clinicians

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