Gross hematuria is a rare and unusual clinical finding in patients with infectious mononucleosis; however, the renal tract may be involved in the course of this disease. Tidy and Morley reported an incident of renal involvement in 6% of 270 cases analyzed in 1921. Wechsler noted abnormal urinary findings in 3% of 556 cases observed during an Army epidemic. This 3% included patients with red and white blood cells, albumin, hyaline, and granular casts in the urine and included two cases of gross hematuria. Thompson and Pitt reported a case of infectious mononucleosis with gross hematuria occurring in an 18-year-old college girl. However, many series of cases reported in the literature over a period of years either make no mention of renal findings or stated that none were noted. This case of a patient with infectious mononucleosis is presented to emphasize that gross hematuria may be an outstanding feature, since
Lindsey DC, Chrisman WP. GROSS HEMATURIA AS THE PRESENTING SYMPTOM OF INFECTIOUS MONONUCLEOSIS. JAMA. 1955;157(16):1406. doi:10.1001/jama.1955.02950330046008a
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