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May 14, 1955

Bone: An Introduction to the Physiology of Skeletal Tissue

JAMA. 1955;158(2):149. doi:10.1001/jama.1955.02960020055029

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Smoothly written and attractively printed, this book summarizes what is known about the structure and function of human bone. In the hands of the authors, what could be a dull subject becomes extremely interesting. After the opening chapters on the cellular anatomy and physiology involved, successive chapters deal with the intercellular structure of organic matrix and inorganic salts; the dynamics of calcification; the enzymes active in deposition and resorption of bone; the influence of systemic and local factors, especially hormones, in bone growth; the metabolism of calcium, phosphate, and citrate in relation to bone; the effects of ionizing radiation; the phenomena of osteogenesis in explants and transplants; the healing of fractures; and the abnormalities caused by disease. The data include some of the most recent results of using radioactive isotopes as tracers, and the illustrations include beautiful examples of electron microscopy and radioautography. There is a bibliography and an index.

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