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The fundamentals of prescription writing would seem to preclude radical change. But striking changes have taken place, as seen in the growing tendency to use the metric system in the substitution of English titles for the Latin by the Pharmacopoeia, the National Formulary and in prescriptions, in the dropping of the old galenicals and their replacement by chemical drugs and active principles, in the tendency to prescribe potent drugs by themselves rather than in a shotgun mixture and in the extensive employment of hypodermic and intravenous administration. We must still write prescriptions, but the finished prescription differs from that of thirty years ago.
While the author has devoted much space, as in previous editions, to the prescription in Latin, he has added a whole chapter on The Modern Prescription, and out of the old has graduated into the new as a matter of evolution. He accepts "about 5 cc."
Essentials of Prescription Writing. JAMA. 1948;137(13):1174. doi:10.1001/jama.1948.02890470074047
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