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July 2, 1955

Ciba Foundation Symposium on Chemistry and Biology of Pteridines

JAMA. 1955;158(9):798. doi:10.1001/jama.1955.02960090092028

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This symposium is the 25th in the series. The Ciba Foundation, established as an educational and scientific charity under the laws of England, is an international center where research workers from different countries are invited to participate in symposiums. The present volume contains a review of the available information as well as original material. This characteristic together with the discussion of the individual papers should make the book a valuable asset to anyone interested in pteridine-like compounds. The book is well illustrated with diagrams, graphs, and tables.

Topics included in the chemistry of pteridines are: ring-opening reactions, alkylation, ultraviolet absorption spectrums, chromatography, and electrophoretic studies of pteridines, constitution of urothione, pteridines of Drosophila melanogaster, sulfonamide derivatives of pteridines, use of o-aminonitroso compounds in the synthesis of rings, recent developments in pteridine synthesis, and some unresolved problems. Included in the biological aspects of pteridines are: metabolic relations of p-aminobenzoic

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