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Article
September 25, 1948

The Pathology of Nutritional Disease: Physiological and Morphological Changes Which Result from Deficiences of the Essential Elements, Amino Acids, Vitamins, and Fatty Acids

JAMA. 1948;138(4):327. doi:10.1001/jama.1948.02900040071028

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Abstract

This readable and not too lengthy monograph is a scholarly and critical review of current knowledge of nutritional disease. The main emphasis is on the morphologic end results of the deficiencies, with perhaps less attention paid to biochemistry and physiology than some would like. Each of the forty or more indispensable nutrients is treated separately. Seventeen or eighteen of the ninety-odd metallic and nonmetallic elements are included, as well as ten of the twenty-odd amino acids, three closely related fatty acids and fifteen vitamins, in which there is evidence in one or more species for indispensability. The abnormalities in mammals provoked by deficiencies of these several substances are described. Illustrations add to the value of the book. They are numerous and excellent. Many of them are original. The bibliography of about 800 references covers most of the important literature. Although little attention is given to diagnosis of nutritional disease in

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