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August 27, 1955

The Biologic Effects of Tobacco with Emphasis on the Clinical and Experimental Aspects

JAMA. 1955;158(17):1573. doi:10.1001/jama.1955.02960170089040

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The expressed purpose of this book is to determine what is fact and what is fancy about the possible relationship of tobacco and tobacco smoke to human health. The evidence for and against smoking as a calculated risk to health is assembled in eight well-written, well-documented chapters. These deal with the chemistry and pharmacology of tobacco and its relationship to the cardiovascular system, neoplastic diseases, the gastrointestinal tract, and allergic phenomena. An important chapter, called Cause and Effect, dwells on the significance of statistics in establishing some of the associations described.

For some time medical and public attention has been focused on the relationship of smoking and cancer of the lung. There has been a tendency to overlook some of the other effects of smoking on human health, which, in the long run, may eventually prove more significant than the question of lung cancer. For example, relatively little attention has

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