Peptic ulcer is a classic example of a somatic disease which is greatly influenced by and possibly precipitated by psychic factors. All physicians have been impressed by the close relationship between nervousness, anxiety, worry or psychic trauma and the acute exacerbations of ulcer but we are apt to forget the admonition of Jordan1 that there may be a somatopsychic as well as a psychosomatic interplay. The typical spring and fall exacerbations without obvious precipitating causes may result in worry, anxiety and nervous tension which in a sick person bring about family quarrels, business worries, fear of losing a job or other problems that are sure to aggravate any symptoms the unhappy victim may have.
The principal changes in the management of peptic ulcer in the last decade have not been primarily changes in diagnostic methods, but in the handling of the ulcer after the diagnosis is made. It is
WILKINSON SA. PRESENT STATUS OF THE PEPTIC ULCER PROBLEM. JAMA. 1948;138(11):805–807. doi:10.1001/jama.1948.02900110015005
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