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Article
November 20, 1948

CLINICAL MANIFESTATIONS OF INFECTION WITH POLIOMYELITIS VIRUS

Author Affiliations

Birmingham, Ala.; Chicago; Birmingham, Ala.; Chicago

From the laboratories of the Chicago Health Department, The Birmingham Baptist Hospitals and the Department of Bacteriology, University of Chicago.

JAMA. 1948;138(12):865-869. doi:10.1001/jama.1948.02900120007002
Abstract

Most of the clinical observations on poliomyelitis have been limited to that relatively rare form of the disease which results in residual paralysis. Even here no controlled observations have been published which enable one to say whether a great variety of symptoms are really typical of this disease. For instance, current articles in the foreign and American literature list diarrhea, sore throat, running nose and cough as symptoms of poliomyelitis, but offer no proof. It may be said with safety that outside of paralysis or paresis in a child with an acute febrile illness resulting in head drop, stiff neck and stiff back, and usually accompanied with moderate increase in the spinal fluid protein or cells, no symptoms have been firmly established. Children without these signs from whom the virus has been recovered have often been erroneously called "healthy carriers."

In the special survey of poliomyelitis which has been conducted

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